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Meg Ryan has published a heartfelt tribute to the departed director Rob Reiner, who directed her in the hit romantic comedy When Harry Met Sally.

A Devastating Incident

Reiner was discovered deceased alongside his spouse, Michele Singer Reiner, at their residence in LA over the weekend.

“We will miss this man so deeply…” Ryan shared on Instagram, next to an image of them together. “We thank you, Rob and Michele, for your belief in true love, fairy tales, and laughter. Your trust in people's goodness and your love for this nation are remembered.”

Court Case Developments

Reiner’s son Nick, 32, has been charged with two counts of first-degree murder and appeared in court today. He’s being held without bail. Reports indicate that Reiner’s daughter Romy discovered her father deceased.

“I have to believe that their story will not end with this impossible tragedy, that some good may come, some awareness raised,” Ryan went on to write. “While uncertain, I suspect they'd wish for a hopeful, compassionate outcome that fosters mutual understanding and peace.”

Family Members Issue a Message

Reiner’s other children Jake and Romy released a message today. “Language fails to capture the daily agony we endure,” they said. “The horrific and devastating loss of our parents, Rob and Michele Reiner, is something that no one should ever experience. They weren’t just our parents; they were our best friends.”

Hollywood Tributes Pour In

Ryan’s co-star, Billy Crystal, joined in remembering Reiner with a statement shared yesterday together with remarks by Larry David, Martin Short and Albert Brooks.

“No one matched his comic instinct, his dedication to rhythmic dialogue, or his elegant sharpening of drama,” it read. “For the actors, he loved them. For the writers he made them better. His greatest gift was freedom. If you had an idea, he listened, he brought you into the process. They always felt they were working as a team. To be in his hands as a film-maker was a privilege but that is only part of his legacy.”

A Lasting Cinematic Legacy

When Harry Met Sally was a box office and critical triumph in 1989, making over $93m at the box office and earning Nora Ephron an Oscar nomination for best original screenplay.

Rob Reiner was introduced to Michele Singer Reiner during the production of When Harry Met Sally. The pair were brought together by Barry Sonnenfeld, a director and friend.

Reiner’s celebrated filmography also included classics such as Misery, Stand by Me and The Princess Bride. The director and his wife were husband and wife for over three decades.